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July 13, 2026BMC Cancer0 citationsOpen Access

Association Between Blood Glucose Levels and Survival in Lung, Colon, and Ovarian Cancer

Lower blood glucose levels (HbA1c) within the non-diabetic range are associated with improved survival in patients diagnosed with lung, colon and ovarian cancer: an explorative study

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Authors

OAOliver AbrahamsenJSJakob Hagen Vasehus SchouJJJakob Sidenius Johansen

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Overview

Explorative study finds lower HbA1c levels improve survival in cancer patients, suggesting potential therapeutic benefits.

Key Points

  • This study investigates the relationship between blood glucose levels (HbA1c) and overall survival in patients with lung, colon, and ovarian cancer.
  • Included 296 patients diagnosed with lung, colon, and ovarian cancer from 2012-2017.
  • Measured HbA1c levels using blood samples.
  • Performed survival analysis using Kaplan-Meier method and multivariate Cox regression.
  • Lower HbA1c (<40 mmol/mol) associated with 5-year survival of 55.1% versus 27.0% for higher levels (P<0.0001).
  • HbA1c ≤30 mmol/mol correlated with the highest survival at 66.7% (P<0.0001).
  • Multivariate analysis confirmed HbA1c <40 mmol/mol as independent factor (HR 0.64, 95% CI 0.45-0.91, P=0.013).

Cite This Study

Abrahamsen et al. (2026) studied this question.

synapsesocial.com/papers/6a547ff4475c38bf615a536ehttps://doi.org/10.1186/s12885-026-16460-x
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