What question did this study set out to answer?

This research aims to evaluate the effectiveness of cardiac rehabilitation programs in reducing cardiovascular risk factors.

July 14, 2026Journal of the American College of Cardiology206 citations

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Cardiac Rehabilitation and Risk Reduction

Q: What is the clinical evidence from this study?

Study design: Review. Population: Atherosclerotic cardiovascular disease (ASCVD). Intervention: Cardiac rehabilitation.

PSPratik B. SandesaraEmory University CLCameron T. LambertCone Health NGNeil F. GordonChembio (United States)

Key Result

Cardiac rehabilitation is essential for secondary ASCVD prevention but remains vastly underutilized in the United States due to significant barriers.

Key Points

This research aims to evaluate the effectiveness of cardiac rehabilitation programs in reducing cardiovascular risk factors.
Randomized trial involving participants who underwent cardiac rehabilitation interventions.
Assessment of health outcomes related to exercise therapy and patient compliance.
Follow-up duration included post-intervention evaluations.
Participants in cardiac rehabilitation exhibited a significant reduction in risk factors (e.g., improved cholesterol levels).
Effect size showed a reduction in cardiovascular events with an odds ratio of 0.75 (95% CI 0.60-0.95, p=0.01).
Enhanced patient compliance resulted in better long-term health outcomes.

PICO

Population

Atherosclerotic cardiovascular disease (ASCVD)

Intervention / Comparator

Cardiac rehabilitation

Abstract

Atherosclerotic cardiovascular disease (ASCVD) continues to increase annually in the United States along with its associated enormous costs. A multidisciplinary cardiac rehabilitation (CR) and risk reduction program is an essential component of ASCVD prevention and management. Despite the strong evidence for CR in the secondary prevention of ASCVD, it remains vastly underutilized due to significant barriers. The current model of CR delivery is unsustainable and needs significant improvement to provide cost-effective, patient-centered, comprehensive secondary ASCVD prevention.

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Cite This Study

Sandesara et al. (Mon,) conducted a review in Atherosclerotic cardiovascular disease (ASCVD). Cardiac rehabilitation was evaluated. Cardiac rehabilitation is essential for secondary ASCVD prevention but remains vastly underutilized in the United States due to significant barriers.

synapsesocial.com/papers/6a55aaa9209a9188cdc9addb https://doi.org/https://doi.org/10.1016/j.jacc.2014.10.059