Key result
Takotsubo syndrome is a heterogeneous acute heart failure syndrome affecting both sexes, triggered by physical or emotional stress, and carries a substantial risk of morbidity and mortality.
Why the study?
Commonly held beliefs that Takotsubo syndrome predominantly affects postmenopausal women after emotional stress may contribute to underdiagnosis and misperception of the condition.
Takotsubo syndrome is a heterogeneous condition affecting diverse demographics with significant physical triggers and long-term symptoms, challenging historical misconceptions.
Challenges historical TTS misconceptions; leaves open optimal long-term management strategies.
PURPOSE OF REVIEW: Takotsubo syndrome (TTS) was described in Japan 3 decades ago to affect predominately postmenopausal women after emotional stress. This history is the basis of commonly held beliefs which may contribute to the underdiagnosis and misperception of TTS. RECENT FINDINGS: TTS affects not only women, but can be present in both sexes, and can appear in children as well as in the elderly. TTS is characterized by unique clinical characteristics with morphological variants, and incurs a substantial risk for recurrent events and adverse outcomes. Physical triggers are more common than emotional triggers and are major disease determinants. TTS seems not to be completely transient as patients report ongoing chest pain, dyspnea, or fatigue even after months of the acute event. Knowledge of the clinical features and outcomes of TTS patients has evolved substantially over the past decades. The heterogeneous appearance of TTS needs to be recognized in all medical disciplines to maximize therapy and improve outcomes.
No takes yet. Share an insight, caveat, or question.
Cammann et al. (2021) conducted a review in Takotsubo syndrome. Takotsubo syndrome is a heterogeneous acute heart failure syndrome affecting both sexes, triggered by physical or emotional stress, and carries a substantial risk of morbidity and mortality.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: