The overall prevalence of chronic kidney disease stages 1-5 in the general adult population in Africa was 15.8%, with an even higher prevalence of 32.3% in high-risk populations.
Meta-Analysis (n=98,432)
Chronic kidney disease is highly prevalent across Africa, with an overall prevalence of 15.8% for stages 1-5 in the general population, highlighting a critical need for prevention and early detection in resource-limited settings.
Estimación del efecto: 15.8% prevalence (95% CI 12.1-19.9)
Accurate contemporary data on the burden of Chronic Kidney Disease (CKD) on the African continent are lacking. We determined the prevalence of CKD in adult populations living in Africa, and variations by stage, gender, estimated Glomerular Filtration Rate (eGFR) equation, and residence. For this systematic review, we searched multiple electronic databases for original studies on CKD prevalence reported from January 1, 2000 to December 31, 2016. Two reviewers independently undertook quality assessment and data extraction. We stabilized the variance of study-specific estimates with the Freeman-Turkey single arcsine transformation and pooled the data using a random effects meta-analysis models. A total of 98 studies involving 98,432 individuals were included in the final meta-analysis. The overall prevalence was 15.8% (95% CI 12.1–19.9) for CKD stages 1–5 and 4.6% (3.3–6.1) for CKD stages 3–5 in the general population. Equivalent figures were greater at 32.3% (23.4–41.8) and 13.3% (10.7–16.0) in high-risk populations (people with hypertension, diabetes, HIV). CKD prevalence was higher in studies based on the Cockcroft-Gault formula than MDRD or CKD-EPI equations; and in studies from sub-Saharan Africa compared with those from North Africa (17.7, 95% CI 13.7–22.1 vs 6.1, 95% CI 3.6–9.3, p 90%) and no evidence of publication bias in main analyses. CKD is highly prevalent across Africa, inviting efforts into prevention, early detection and control of CKD in adults living on the African continent which is particularly important in a resource limited environment. Prospero Registration ID: CRD42017054445 .
Kazé et al. (Fri,) conducted a meta-analysis in Chronic Kidney Disease (n=98,432). Adult populations living in Africa was evaluated on Overall prevalence of CKD stages 1-5 in the general population (15.8% prevalence, 95% CI 12.1-19.9). The overall prevalence of chronic kidney disease stages 1-5 in the general adult population in Africa was 15.8%, with an even higher prevalence of 32.3% in high-risk populations.
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