Lactiplantibacillus plantarum WJL ameliorates chronic kidney disease by inhibiting fibroblast growth factor 21 adaptive stress response via low protein diet

Key Points

The aim is to determine the effects of Lactiplantibacillus plantarum WJL on chronic kidney disease by assessing its impact on the fibroblast growth factor 21 response to low protein diets.
Supplementation of Lactiplantibacillus plantarum WJL in a controlled dietary setting
Monitoring the adaptive stress response related to fibroblast growth factor 21
Assessing clinical outcomes in chronic kidney disease management
Significant improvement in kidney function markers observed with L. plantarum WJL supplementation
Reduction in fibroblast growth factor 21 activity noted with low protein diet alongside probiotic treatment
Potential enhancements in patient quality of life as indicated by clinical assessments

Shows improved outcomes in chronic kidney disease, suggesting dietary strategies may enhance management.

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Benoit et al. (2026) studied this question.

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