Key result
MASLD with low handgrip strength linked to higher 10-year ASCVD risk.
Why the study?
Does the presence of MASLD and low handgrip strength increase the risk of ASCVD in the general population?
Cross-Sectional (n=20,611)
Does the presence of MASLD and low handgrip strength increase the risk of ASCVD in the general population?
The combination of MASLD and low handgrip strength is associated with a significantly higher estimated 10-year risk of ASCVD in the general population.
Background: We aimed to investigate the influence of metabolic dysfunction-associated steatotic liver disease (MASLD) and handgrip strength (HGS) on the risk of atherosclerotic cardiovascular disease (ASCVD) in the general population. Methods: We used data from 20,611 individuals from the 2014-2019 Korea National Health and Nutrition Examination Survey. MASLD was defined as a Framingham steatosis index of ≥23. Low HGS was defined as <28 kg in men and <18 kg in women. The 10-year ASCVD risk score was assessed, and high-probability ASCVD was defined as >10%. Conclusion: Individuals with MASLD and low HGS had a significantly higher risk of ASCVD than those without MASLD. Concurrent advanced liver fibrosis was further associated with increased ASCVD risk among individuals with MASLD.
No takes yet. Share an insight, caveat, or question.
Han et al. (2026) conducted a cross-sectional in General population (n=20,611). Metabolic dysfunction-associated steatotic liver disease (MASLD) and low handgrip strength vs. Individuals without MASLD was evaluated on High-probability ASCVD (10-year ASCVD risk score >10%) (p=<0.001). Individuals with MASLD and low handgrip strength had a significantly higher risk of atherosclerotic cardiovascular disease than those without MASLD (P<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: