Key result
Concomitant heart failure in self-transported AMI is linked to an ~7-fold increase in in-hospital mortality.
Why the study?
Rapid access to EMS is essential to improve AMI outcomes, but the outcomes of patients with AMI who are not transported by EMS remain unclear.
Does concomitant heart failure increase in-hospital mortality in patients with acute myocardial infarction who self-transport to the hospital?
Observational (n=124,942)
Yes
Does concomitant heart failure increase in-hospital mortality in patients with acute myocardial infarction who self-transport to the hospital?
Answers are grounded in this paper and cite their sources.
Nearly 15% of AMI patients who self-transport to the hospital present with concomitant heart failure, representing a high-risk subgroup with significantly elevated in-hospital mortality (8.6%) that requires targeted prehospital education and care strategies.
Background: Rapid access to emergency medical services (EMS) is essential to improve outcomes in patients with acute myocardial infarction (AMI). However, the outcomes of patients with AMI who are not transported by EMS remain unclear. Methods and Results: Patients who self-transported to hospital were classified into 2 groups according to Killip classification at the time of admission: those with heart failure (HF; Killip III or IV) and those without HF (Killip I or II). We assessed temporal trends in self-transport and compared patient characteristics and in-hospital mortality between the 2 groups. In all, 124,942 patients self-transported to hospital, of whom 18,342 (14.7%) were classified having HF. The proportion of patients self-transporting to hospital decreased from 35.3% in 2012 to 24.8% in 2023. Factors associated with self-transport with HF included older age (odds ratio [OR] 1.18; 95% confidence interval [CI] 1.17–1.20), female sex (OR 1.10; 95% CI 1.06–1.14), admission to non-training facilities (OR 1.49; 95% CI 1.29–1.73), and weekend admission (OR 1.09; 95% CI 1.04–1.13). In-hospital mortality was recorded for 2,599 (8.6%) and 1,265 (1.3%) self-transported patients with and without HF, respectively. Conclusions: Of self-transported patients with AMI, 14.7% had concomitant HF, highlighting a clinically non-negligible subgroup requiring careful attention.
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Takegawa et al. (2026) conducted an observational in Acute Myocardial Infarction (n=124,942). Concomitant heart failure (Killip III or IV) vs. No heart failure (Killip I or II) was evaluated on In-hospital mortality. Among self-transported patients with acute myocardial infarction, 14.7% presented with concomitant heart failure, which was associated with a substantially higher in-hospital mortality rate (8.6%) compared to those without heart failure (1.3%).
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