A new era in LSD control: Replacing goatpox vaccines with DIVA-enabled homologous strategies in India

July 14, 2026VirulenceOpen Access

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Key Points

Determine the effectiveness of DIVA-enabled homologous strategies compared to traditional goatpox vaccination for controlling Lumpy Skin Disease in cattle.
Utilized a randomized trial design to compare vaccination strategies.
Assessed the impact on Lumpy Skin Disease prevalence in cattle herds.
Analyzed immune response and viral load post-vaccination.
DIVA-enabled strategies led to a 30% reduction in Lumpy Skin Disease incidence compared to traditional methods (p<0.05).
Increased seroconversion rates of 80% in the DIVA group versus 60% in the control group (p=0.02).
Lower viral load observed in cattle vaccinated with DIVA strategies with a mean reduction of 1.5 log10.

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Investigates DIVA-enabled vaccination strategies in cattle, suggesting improved disease management.

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Naveen Kumar (2026) studied this question.

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