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Examines cucumber treatments for delaying senescence and extending lifespan in C. elegans, suggesting novel anti-aging applications.
The research examines the potential of cucumbers treated with sorbitol (SL) and methyl salicylate (MS) at concentrations ranging from 10 μM:10–30 μM:30 μM, and at 10 μM each, as anti‐ageing agents. The cucumbers were then refrigerated at ± 4°C after treatment. Across all treatments, total soluble sugar, proline, and DPPH activity increased, while protein and peroxidase activity decreased, indicating that the fruits maintained their natural post‐harvest character. Notably, the lifespan of Caenorhabditis elegans , a nematode sharing 83% of its proteome with humans, was significantly extended after it was treated with a solution derived from the supernatant of peeled cucumbers. This groundbreaking study opens new avenues for extending lifespan and sheds light on the problem of aging, pointing to cucumbers' potential as anti‐ageing agents.
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Trivedi et al. (2026) studied this question.
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