Water‐based DNF @ PLA microcapsules with excellent interface properties enhancing insecticidal activity against Nilaparvata lugens

BACKGROUND Dinotefuran (DNF) is a third‐generation neonicotinoid and renders broad‐spectrum efficacy against piercing‐sucking pests. Among these, Nilaparvata lugens , one of the most destructive piercing‐sucking pests, is highly susceptible to DNF. However, traditional DNF formulations tend to leach out and exhibit a low utilization rate. This work developed microcapsules using water‐in‐oil (W/O) emulsions as templates in combination with the eco‐friendly material polylactide (DNF@PLA). RESULTS This study employed a variable‐controlled method to prepare DNF@PLA. The drug loading and encapsulation efficiency of DNF@PLA were 11.13% and 77.52%, respectively. Compared to commercial suspension agent (SC), DNF@PLA exhibited excellent temperature responsiveness and a 30% improvement in photodegradation resistance. The DNF@PLA exhibited superior control efficacy against Nilaparvata lugens (LC 50 = 0.397 mg L −1 ) than the commercial SC (LC 50 = 0.646 mg L −1 ). CONCLUSION This study demonstrated that DNF@PLA exhibited superior interfacial properties and insecticidal efficacy, enabling reduced surfactant requirements and promising practical applications.