Retrospective case series finds extended-release buprenorphine supports treatment stability in adults with opioid use disorder from poppy seed tea.
BACKGROUND AND OBJECTIVES: Poppy seed tea (PST) contains unpredictable opioid concentrations, destabilising tolerance and increasing overdose risk. Extended-release buprenorphine (BUP-XR) provides sustained coverage without daily dosing. METHODS: Eighteen-month follow-up of adults (N = 3) with opioid use disorder (OUD) involving PST in Australia. RESULTS: All had polysubstance use and transitioned to BUP-XR after 2 days to 6 months of sublingual buprenorphine. Posttransition urine drug screens were morphine-negative; one patient was intermittently tramadol-positive. All remained in treatment at 18 months. DISCUSSION AND CONCLUSIONS: BUP-XR assisted stability within multidisciplinary care. SCIENTIFIC SIGNIFICANCE: This series adds longer-term follow-up on PST-related OUD and suggests BUP-XR feasibility.
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