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July 18, 2026Perioperative Medicine0 citationsOpen Access

Effectiveness of safety care and clinical nursing pathway in patients undergoing cardiovascular intervention: a randomized controlled trial

YXYinhua XiTYTongqing YaoZCZHANG Cuicui

Key Result

Safety care and clinical nursing pathways significantly reduced post-intervention anxiety (HAMA 6.42 vs 9.24) and depression (HAMD 6.32 vs 8.76) compared to standard care (p<0.05).

Key Points

  • The aim was to assess the effectiveness of safety care and clinical nursing pathways on anxiety, depression, and recovery in cardiovascular patients.
  • Single-center, single-blind, randomized controlled trial
  • 100 patients underwent cardiovascular intervention, with 50 in each control and experimental group
  • Outcomes assessed included anxiety and depression, recovery time, surgery time, success rates, and quality of life measures.
  • Post-intervention HAMA scores were significantly lower in the experimental group (6.42) compared to the control group (9.24), p < 0.05.
  • Adverse reactions occurred in 12.0% of the experimental group vs. 30.0% in the control group, p < 0.05.
  • Surgery time was shorter in the experimental group (45.60 min) compared to the control group.

Study Design

Type

RCT (n=100)

Blinding

Single-blind

Randomization

randomly assigned

Multicenter

No

Structured PICO

Does safety care and clinical nursing pathway improve anxiety and depression symptoms in patients undergoing cardiovascular intervention?

P
Population
100 patients undergoing cardiovascular intervention.
I
Intervention
Safety care and clinical nursing pathway interventions in addition to standard care
C
Comparator
Standard nursing care
O
Outcome
Anxiety and depression symptoms assessed using the Hamilton Anxiety and Hamilton Depression (HAMA and HAMD) rating scalespatient reported

Implementing safety care and clinical nursing pathways significantly reduces anxiety and depression, lowers adverse reactions, and improves procedural efficiency and patient satisfaction in patients undergoing cardiovascular interventions.

Main Result

Absolute Event Rate: 6.42% vs 9.24%

p-value: p=<0.05

Abstract

This study aimed to investigate the effectiveness of safety care and clinical nursing pathways in patients undergoing cardiovascular intervention. This single-center, single-blind, randomized controlled trial enrolled 100 patients who underwent cardiovascular intervention. Patients were randomly assigned to a control group (receiving standard nursing care) or an experimental group (receiving safety care and clinical nursing pathway interventions in addition to the standard care) ( n = 50 each). The primary outcome measure included anxiety and depression symptoms assessed using the Hamilton Anxiety and Hamilton Depression (HAMA and HAMD) rating scales. Secondary outcome measures included cardiac function recovery time, surgery time, surgical vascular puncture success rate, puncture preparation time, and hospital stay, along with adverse events and complications, quality of life, and nursing satisfaction. In the experimental group, post-intervention HAMA (6.42 ± 2.41) and HAMD (6.32 ± 1.44) scores were significantly lower than those in the control group (9.24 ± 1.52, 8.76 ± 1.59) ( p < 0.05). The incidence of adverse reactions was lower in the experimental group (12.0%) than in the control group (30.0%) ( p < 0.05). Surgery time (45.60 ± 2.98 min) and puncture preparation time (5.08 ± 1.09 min) were shorter, and the vascular puncture success rate was higher (96.0%) in the experimental group; quality-of-life scores and nursing satisfaction were also higher in the experimental group ( p < 0.05). Safety care and clinical nursing pathways may be effective in reducing anxiety and depression, lowering adverse reactions, shortening operation and puncture preparation times, increasing the success rate of vascular puncture, improving health knowledge, boosting patient satisfaction, and enhancing quality of life in patients undergoing cardiovascular intervention.

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Cite This Study

Xi et al. (2026) conducted an RCT in Cardiovascular intervention (n=100). Safety care and clinical nursing pathway vs. Standard nursing care was evaluated on Anxiety and depression symptoms assessed using HAMA and HAMD rating scales (p=<0.05). Safety care and clinical nursing pathways significantly reduced post-intervention anxiety (HAMA 6.42 vs 9.24) and depression (HAMD 6.32 vs 8.76) compared to standard care (p<0.05).

synapsesocial.com/papers/6a5b39118167787360d24e9ehttps://doi.org/10.1186/s13741-026-00718-w
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