Modern Palladium-Catalyzed Transformations Involving C–H Activation and Subsequent Annulation

The metal-catalyzed “cascade C–H activation/annulation” is a highly promising approach to the construction of aromatic and heteroaromatic compounds. In this context, Pd-complexes play a crucial role whereby molecules bearing a directing group can be activated with high catalytic efficiency. These reactions will expand the synthetic potential of Pd-catalyzed C–H activation and subsequent aromatic and aliphatic C–C bond formation. Described herein is an outline of the recent advances in this research subject.