Radicals derived from N,N-disubstituted o-iodobenzamides undergo rapid 1,5-hydrogen-transfer reactions. The regioselectivity of these reactions is coupled to the rotamer population of the starting iodobenzamide, and the products vary with changing amide substituents. Related 1,5-hydrogen-transfer reactions are observed for N-alkyl-N-(o-iodobenzyl)-benzamides and -acetamides.
No takes yet. Share an insight, caveat, or question.
Curran et al. (1994) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: