Key result
Combining oral hypoglycemic agents with insulin is linked to ~3.8-fold higher odds of poor glycemic control.
Cross-Sectional (n=364)
Answers are grounded in this paper and cite their sources.
Background: Diabetes is a public health problem of colossal proportions. The National Family Health Survey 5 (2019-2020) has found high blood sugar levels among 13.5% of women and 15.6% of men in India. The high morbidity and mortality in diabetes mellitus are due to uncontrolled hyperglycemia resulting in micro- and macrovascular changes affecting multiple organs in the body. The objectives of this study were to estimate glycemic control and its determinants among type 2 diabetics in the Ernakulam district. Methods: A community-based cross-sectional study was conducted among 364 type 2 diabetics who had the disease for at least 5 years duration in the Ernakulam district of Kerala. Probability proportional to size cluster sampling technique was adopted. A semi-structured questionnaire was used to collect sociodemographic and behavioral profiles. Participants' HbA1c levels were assessed to determine glycemic control. Results: (aOR = 2.71, P = 0.002), combined drug treatment with Oral Hypoglycaemic agents (OHA) and insulin (aOR = 3.76, P = 0.004), and poor compliance with medications (aOR = 1.93, P = 0.030) were found to be significantly associated with poor glycemic control. Conclusions: Poor compliance with medications and unhealthy lifestyle choices has resulted in a high proportion of diabetics with poor glycemic control in the district. Women are particularly more vulnerable to uncontrolled hyperglycemia than males. Type 2 diabetes mellitus people should be encouraged to maintain strict glycemic control, which is an important measure for secondary prevention of complications.
No takes yet. Share an insight, caveat, or question.
Joy et al. (2022) conducted a cross-sectional in Type 2 diabetes mellitus (n=364). Combined oral hypoglycaemic agents (OHA) and insulin vs. Other treatment regimens was evaluated on Poor glycemic control (aOR 3.76, p=0.004). Combined treatment with oral hypoglycaemic agents and insulin (aOR 3.76, P=0.004) and poor medication compliance (aOR 1.93, P=0.030) were significantly associated with poor glycemic control.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: