The effect of a behavioral activation treatment for substance use on post‐treatment abstinence: a randomized controlled trial

AIMS: To compare outcomes for a behavioral activation group treatment for substance use life enhancement treatment for substance use (LETS ACT) versus a time and group size-matched control condition delivered in a residential treatment setting. DESIGN: Single-site two-arm parallel-group randomized clinical trial with follow-up assessment at 3, 6 and 12 months post-treatment. SETTING: Residential substance use treatment facility in the United States. PARTICIPANTS: Participants were 263 adults mean age 42.7 (11.8); 29.5% female; 95.4% African American; 73.2% court mandated whose insurance dictated 30-day (65.9%) or 90-day (34.1%) treatment duration. INTERVENTION AND COMPARATOR: LETS ACT (n = 142) is a treatment developed originally for depression and modified for substance use. It teaches participants to increase positively reinforcing value-driven activities in order to counter depression and relapse. The control group supportive counseling (SC); n = 121 received time and group size-matched supportive counseling. Treatment was delivered in five or eight 1-hour sessions depending on patient length of stay. MEASUREMENTS: Percentage abstinent at follow-up, percentage of substance use days among those reporting use, depressive symptoms Beck Depression Inventory (BDI) and adverse consequences of drug use Short Inventory of Problems-Alcohol and Drug (SIP-AD). FINDINGS: LETS ACT had significantly higher abstinence rates at 3 months odds ratio (OR) = 2.2, 95% confidence interval (CI) = 1.3-3.7, 6 months (OR = 2.6, 95% CI= 1.3-5.0) and 12 months (OR = 2.9, 95% CI = 1.3-6.1) post-treatment compared with SC. LETS ACT participants reported significantly fewer adverse consequences from substance use at 12 months post-treatment B = 4.50, standard error (SE) = 2.17, 95% CI = 0.22-8.78. Treatment condition had no effect on percentage substance use days among those who resumed use or on change in depressive symptoms; the latter decreased over time only in those who remained abstinent after residential treatment irrespective of condition (B = 0.43, SE = 0.11, 95% confidence interval = 0.22-0.65). CONCLUSIONS: A behavioral activation group treatment for substance use (LETS ACT) appears to increase the likelihood of abstinence and reduce adverse consequences from substance use up to 12 months post-treatment.