Key result
Emerging therapies target neuroanatomical plasticity to improve functional recovery following stroke.
Ischemic stroke affects many new patients each year. The sequelae of brain ischemia can include lasting sensorimotor and cognitive deficits, which negatively impact quality of life. Currently, treatment options for improving poststroke deficits are limited, and the development of new clinical alternatives to improve functional recovery after stroke is actively under investigation. Anti-Nogo-A immunotherapy to reduce the central nervous system inhibitory environment, cell transplantation strategies, pharmacological agents, and movement-based therapies represent emerging treatments of poststroke deficits through enhancement of neuroanatomical plasticity.
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Cheatwood et al. (2008) conducted a review in Ischemic stroke. Emerging treatments (Anti-Nogo-A immunotherapy, cell transplantation, pharmacological agents, movement-based therapies) was evaluated. Emerging treatments, including anti-Nogo-A immunotherapy, cell transplantation, and movement-based therapies, aim to improve poststroke functional recovery through neuroanatomical plasticity.
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