The efficient tandem rhodium‐catalysed 1,4‐addition/cyclisation of 1,1′‐alkenes using arylzinc chlorides is described. The simple one‐step synthesis of substituted cyclopentanone and cyclohexanone derivatives is performed from acyclic precursors using relatively low catalyst loadings under mild conditions. A new quaternary carbon centre is created during the cyclisation step.
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Nôtre et al. (2007) studied this question.
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