Key result
Higher myocardial work efficiency was associated with lower in-hospital mortality in COVID-19 patients, with a 13% lower odds of death per 1% increase in efficiency (OR 0.87).
Why the study?
Although troponin elevation is common in COVID-19, the extent of myocardial dysfunction and its contributing factors remain less well-characterized.
Does myocardial work efficiency (MWE) predict in-hospital mortality in hospitalized COVID-19 patients?
Population
136 hospitalized COVID-19 patients undergoing echocardiography
Comparison
Associations of GLS and MWE with in-hospital mortality
Design
Retrospective study
Authors
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Higher MWE was associated with lower COVID-19 mortality; hypothesis-generating for MWE as prognostic marker, needs prospective validation.
Cohort (n=136)
No
Does myocardial work efficiency (MWE) predict in-hospital mortality in hospitalized COVID-19 patients?
Odds Ratio: 0.87 (95% CI 0.78–0.97)
p-value: p=0.009
Subclinical myocardial dysfunction measured by myocardial work efficiency is common in COVID-19 patients and independently associated with in-hospital mortality.
Minhas et al. (2021) conducted a cohort in COVID-19 (n=136). Myocardial work efficiency (MWE) vs. Lower MWE (continuous variable) was evaluated on In-hospital mortality (OR 0.87, 95% CI 0.78-0.97, p=0.009). Higher myocardial work efficiency was associated with lower in-hospital mortality in COVID-19 patients, with a 13% lower odds of death per 1% increase in efficiency (OR 0.87).
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