Key result
A 75% arterial and 25% jugular venous blood contribution ratio provided the lowest root mean square error (2.70) and highest correlation (R2=0.644) with NIRS-determined frontal lobe oxygen saturation compared to the standard 25% arterial calibration ratio.
Meta-Analysis (n=37)
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Sørensen et al. (2014) conducted a meta-analysis in Healthy humans (n=37). 75% arterial and 25% venous reference ratio vs. Standard 25% arterial and 75% venous calibration ratio was evaluated on Root mean square error (RMSE) between NIRS-determined ScO2 and the calculated reference saturation (p=<0.0001). A 75% arterial and 25% jugular venous blood contribution ratio provided the lowest root mean square error (2.70) and highest correlation (R2=0.644) with NIRS-determined frontal lobe oxygen saturation compared to the standard 25% arterial calibration ratio.
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