Hydrogel meets silicone: The chemical functionalization of a polydimethylsiloxane (PDMS) surface with polysaccharide “glue” induces a strong, permanent adhesion between the hydrogel and PDMS. This hydrogel-coated silicone substrate was useful for controlling cellular organization under mechanical stretching (see picture) and also in fabricating microfluidic devices filled with the gel.
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Cha et al. (2013) studied this question.
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