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April 28, 2014Human Reproduction

Regression of endothelial dysfunction in patients with endometriosis after surgical treatment: a 2-year follow-up study

L. Santoro F D'onofrio S. Campo Pietro Manuel Ferraro Andrea Flex Francesco Angelini Floreal H. Forni Erica Nicolardi Vincenzo Campo F. Mascilini Raffaele Landolfi Paolo Tondi Angelo Santoliquido

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Key Points

This research aims to evaluate changes in endothelial function among women with endometriosis following surgical intervention.
Follow-up study involving 68 women, including 22 patients with endometriosis and 10 controls without endometriosis.
Endothelial function assessed using flow-mediated dilation (FMD) two years after surgery.
Serum markers related to endothelial activation and inflammation measured.
FMD increased significantly from baseline by 5.07% in patients with endometriosis (P < 0.001).
No significant change was observed in the control group (1.56%, P = 0.13).
Follow-up FMD values did not differ significantly between groups (1.50%, P = 0.27).

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Implication

Follow-up study shows improvement in endothelial function in women after surgical treatment of endometriosis, suggesting reduced cardiovascular risk.

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Cite This Study

Santoro et al. (2014) studied this question.

synapsesocial.com/papers/6a5c4f6d4a150f8e985ece5d https://doi.org/10.1093/humrep/deu074

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