Impaired Social and Role Function in Ultra-High Risk for Psychosis and First-Episode Schizophrenia: Its Relations with Negative Symptoms

functional level or declining of functional level during few years of follow-up was reported to be significant predictor of transition into overt psychotic disorder. The psychosocial dysfunction in first-episode patients These findings indicate that functional decline may be not chronic illness-related factor or effect of drugs such as antipsychotics rather trait of the disease itself, which can be derived from the lesions of the neurodevelopmental origin. here were some different pictures of psychosocial dysfunction depending on the phase of illness and domains of functioning. The social function in UHR was shown to be significantly compromised, and the extent of impairment was comparable to that of first-episode and multi-episode schizophrenia patients. Meanwhile, role function in UHR was significantly declined to that of first-episode patients but better than