To the Editor: In a letter in the November 5 issue, Alperovitch and Feingold reported an increased sex ratio (male:female) among children of women with multiple sclerosis.1 We have observed a remarkably decreased sex ratio in the offspring of young adults with non-Hodgkin lymphoma. We recorded the sex of the children of 197 patients with this disease who were participating in an epidemiologic study and obtained the same information from a control group of 240 patients without any evident malignant disease. Interviewing the control patients established that they had mainly cardiovascular or respiratory disorders. The results of this study are.
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Olsson et al. (1982) studied this question.
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