Key result
The adult age-adjusted annual incidence of oral anticoagulant-associated intracerebral hemorrhage in the Netherlands was 8.7 per 100,000 person-years (95% CI, 7.3-10.3).
Why the study?
What is the incidence of intracerebral hemorrhage and oral anticoagulant-associated intracerebral hemorrhage in the Netherlands?
Observational (n=652)
Yes
What is the incidence of intracerebral hemorrhage and oral anticoagulant-associated intracerebral hemorrhage in the Netherlands?
The annual incidences of ICH and OAC-ICH in the Netherlands are relatively high compared to international literature, with an absolute risk of OAC-ICH at 0.46% per patient-year.
Answers are grounded in this paper and cite their sources.
Dutch ICH and OAC-ICH incidence estimates may inform local risk assessment; leaves open generalizability and prospective validation.
BACKGROUND AND PURPOSE: The aim of this study was to estimate the annual adult incidence and risk of intracerebral hemorrhage (ICH) and oral anticoagulant-associated ICH (OAC-ICH) in the Netherlands. METHODS: We retrospectively selected all consecutive adult patients with a nontraumatic ICH seen in 1 of 3 hospitals in the region South-Limburg, the Netherlands, from 2007 to 2009. Crude incidences were age-adjusted to Dutch and European population. RESULTS: We identified 652 ICH cases, of which 168 (25.8%) were OAC associated. The adult Dutch age-adjusted annual incidence of ICH and OAC-ICH was 34.8 (95% confidence interval, 32.0-37.8) and 8.7 (95% confidence interval, 7.3-10.3) per 100 000 person-years, respectively. The absolute risk of OAC-ICH was estimated at 0.46% per patient-year of OAC treatment. CONCLUSIONS: The annual incidences of ICH and OAC-ICH are relatively high in the Netherlands when compared with international literature.
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Schols et al. (2013) conducted an observational in Intracerebral hemorrhage (n=652). Oral anticoagulants was evaluated on Annual adult incidence of oral anticoagulant-associated intracerebral hemorrhage per 100,000 person-years (95% CI 7.3-10.3). The adult age-adjusted annual incidence of oral anticoagulant-associated intracerebral hemorrhage in the Netherlands was 8.7 per 100,000 person-years (95% CI, 7.3-10.3).
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