Key result
In human fetuses between 15 and 35 weeks of gestation, the right and left ventricular wall thicknesses grow at the same rate with the right ventricle being only slightly thicker than the left.
Observational (n=14)
No
Unlike the adult heart which has a 3:1 left-to-right ventricular thickness ratio, the fetal heart has almost equal ventricular wall thickness, with the right wall being slightly thicker.
Offers normative fetal ventricular references; leaves open validation against outcomes or pathology.
The difference in the size of the two ventricles in adult is well known and the ratio of left to right ventricular is 3:1, the reason being the difference in the resistance of the two circulations i.e. systemic and pulmonary circulation. However, in fetal life the difference in ventricular size remains unknown. Hence, this study is taken up. The fetal heart of different age group was selected from 15-35 weeks. The thickness of the right and left ventricular walls are measured accurately by using metal callipers and charted out. The difference between the two ventricular wall thickness is very minimal and negligible. The right wall was slightly thicker than the left wall. The shape of the ventricular cavity also looked different as the right cavity is oval while the left cavity looks rounded. The ventricular septum is also mildly covex towards the right side. On the contrary to the findings in adult as 3:1 ratio in terms of ventricular wall thickness the fetal ventricular size remains almost the same. The photographs of horizontal sections just below the coronary sulcus are presented and the increasing size as age advances is presented in details.
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Daimei et al. (2014) conducted an observational in Normal fetal heart development (n=14). Fetal development was evaluated on Right and left ventricular wall thickness. In human fetuses between 15 and 35 weeks of gestation, the right and left ventricular wall thicknesses grow at the same rate with the right ventricle being only slightly thicker than the left.
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