Key result
TEER reduces functional mitral regurgitation and restores large von Willebrand factor multimers.
Why the study?
Does transcatheter edge-to-edge repair (TEER) improve acquired von Willebrand disease and heart failure symptoms in a patient with severe functional mitral regurgitation?
Case Report (n=1)
Does transcatheter edge-to-edge repair (TEER) improve acquired von Willebrand disease and heart failure symptoms in a patient with severe functional mitral regurgitation?
Transcatheter edge-to-edge repair (TEER) may be a viable treatment to manage both heart failure symptoms and acquired von Willebrand disease in patients with severe functional mitral regurgitation.
TEER may reverse acquired von Willebrand disease in functional mitral regurgitation; hypothesis-generating and requires prospective validation before adoption.
A 75-year-old man with a history of small intestinal angioectasia underwent transcatheter edge-to-edge repair for severe functional mitral regurgitation, resulting in recovery of large von Willebrand Factor multimers. This case highlights the potential of transcatheter edge-to-edge repair to manage both heart failure and acquired von Willebrand disease associated with functional mitral regurgitation.
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Obayashi et al. (2024) conducted a case report in Severe functional mitral regurgitation and acquired von Willebrand disease (n=1). Transcatheter edge-to-edge repair (TEER) was evaluated on Recovery of large von Willebrand Factor multimers. Transcatheter edge-to-edge repair successfully reduced functional mitral regurgitation and led to the recovery of large von Willebrand Factor multimers.
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