A general protocol for the challenging cyanofluoroalkylation of unactivated alkenes is disclosed. A broad range of synthetically useful di‐ and mono‐fluorinated alkyl nitriles are readily obtained in good yields under mild reaction conditions. The efficient combination of intramolecular cyano migration and photoredox catalysis significantly expands the field of difunctionalization of olefins. magnified image
No takes yet. Share an insight, caveat, or question.
Ren et al. (2017) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: