Key result
T cell immune responses drive vitiligo pathogenesis, whereas B cell humoral responses are nonessential.
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Lymphocytes are cells within the immune system that originate in the bone marrow (B lymphocytes) or thymus (T lymphocytes). It was thought that lymphocytes are not implied in the pathogenesis of vitiligo, but now we can confirm that T cell response rather than B cell humoral immune response is essential in the pathogenesis of vitiligo.
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Awad et al. (2021) studied this question. T cell immune responses, rather than B cell humoral responses, are essential in the pathogenesis of vitiligo.
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