Ischemic heart disease mortality with documented tobacco use in the US increased significantly from 1999 to 2023, with the age-adjusted rate rising from 3.90 to 32.37 per 100,000 (AAPC 10.71; p<0.01).
Observational (n=1,497,919)
Yes
Ischemic heart disease mortality associated with documented tobacco use has risen sharply in the US from 1999 to 2023, disproportionately affecting older adults, males, and rural populations.
Effect estimate: AAPC 10.71
p-value: p=< 0.01
Abstract Background Tobacco use is a major risk factor for ischemic heart disease (IHD), substantially increasing the likelihood of myocardial infarction, stroke, and premature mortality. This study examined U.S. trends in IHD mortality with documented tobacco use disorder from 1999 to 2023. Methods CDC mortality data for adults aged ≥ 25 years with IHD (ICD-10 codes: I20–I25) and documented tobacco use (ICD-10 code: F17) listed as contributing causes of death were analyzed. Age-adjusted mortality rates (AAMRs) per 100,000 population were calculated. Joinpoint regression was used to estimate annual percent change (APC) and average annual percent change (AAPC). Results From 1999 to 2023, 1,497,919 deaths were reported. The AAMR rose from 3.90 to 32.37 (AAPC: 10.71; p < 0.01). Males had a higher AAMR (39.68; AAPC: 10.72) than females (14.05; AAPC: 10.77). Non-Hispanic (NH) Whites had the highest AAMR (26.86), followed by American Indians (25.43), NH Blacks (19.77), and Hispanics (10.38). The Midwest had the highest regional AAMR (32.96). Most deaths occurred in inpatient facilities (27.9%). Adults aged ≥ 65 years had the highest mortality rate (CMR: 92.16). Rural areas exceeded urban (35.73 vs. 22.95). Conclusion IHD mortality with documented tobacco use has risen sharply, disproportionately affecting older adults, males, rural areas, the Midwest, and NH Whites.
Ibrahim et al. (Sat,) conducted a observational in Ischemic heart disease with documented tobacco use (n=1,497,919). Tobacco use was evaluated on Age-adjusted mortality rates (AAMRs) per 100,000 population (AAPC 10.71, p=< 0.01). Ischemic heart disease mortality with documented tobacco use in the US increased significantly from 1999 to 2023, with the age-adjusted rate rising from 3.90 to 32.37 per 100,000 (AAPC 10.71; p<0.01).