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May 27, 2015Zanco Journal of Medical Sciences1 citationsOpen Access

Ventricular ectopic beats in structurally normal heart: When to stop investigations

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SZSabah Zangana

Key Result

In patients with ventricular ectopic beats and structurally normal hearts, suppression of ectopics by exercise was associated with zero cardiovascular complications over a 5-year follow-up.

Study Design

Type

Cohort (n=50)

Multicenter

No

Structured PICO

Does the suppression of ventricular ectopic beats by exercise predict a benign long-term prognosis in patients with structurally normal hearts?

P
Population
50 adults aged 30-60 years with ventricular ectopic beats, structurally normal hearts, and exercise-suppressible ectopics, followed for 5 years.
E
Exposure
Observation after exercise ECG demonstrating suppression of ventricular ectopic beats
O
Outcome
Relevant complications such as dangerous ventricular arrhythmias, ischemic heart diseases or heart failurehard clinical

Suppression of ventricular ectopic beats by exercise in patients with structurally normal hearts indicates a benign prognosis, precluding the need for further invasive investigations or specific treatment.

Abstract

Background & Objectives: Ventricular ectopic beats (extra systoles, premature beats) are frequently found in healthy people. Ectopic beats in patients without apparent heart disease are more prominent at rest and disappear with exercise. Treatment is not necessary unless the patient is highly symptomatic. Methods: Patients having ventricular ectopic beats were assessed clinically, by ECG and by echocardiography. Those with normal structure hearts underwent exercise ECG and among those we selected 50 patients whose ectopics were suppressed by exercise then followed them for 5 years. The study started from 2000 to 2010. Results: During 5-year follow-up of the above mentioned patients, relevant complications such as dangerous ventricular arrhythmias, ischemic heart diseases or heart failure were not recorded. Conclusions: In patients having ventricular ectopic beats and structurally normal heart, the suppressibilty of the ectopic by exercise indicated their benign origin and may preclude further invasive investigations and even specific treatment.

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Cite This Study

Sabah Zangana (2015) conducted a cohort in Ventricular ectopic beats (n=50). Exercise-suppressed ventricular ectopic beats was evaluated on Cardiovascular complications (dangerous ventricular arrhythmias, ischemic heart diseases, or heart failure). In patients with ventricular ectopic beats and structurally normal hearts, suppression of ectopics by exercise was associated with zero cardiovascular complications over a 5-year follow-up.

synapsesocial.com/papers/6a5dc8a4a5b801175f003430https://doi.org/10.15218/zjms.2015.0011
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Long-Term Follow-up of Asymptomatic Healthy Subjects with Frequent and Complex Ventricular Ectopy1985 · 637 citations
  2. 2Frequency of extrasystoles in healthy male employees.1986 · 35 citations
  3. 3Long-Term Outcome in Asymptomatic Men with Exercise-Induced Premature Ventricular Depolarizations2000 · 291 citations
  4. 4Clinical Correlates and Prognostic Significance of Exercise-Induced Ventricular Premature Beats in the Community2004 · 123 citations
  5. 5The prognostic significance of premature ventricular complexes in adults without clinically apparent heart disease: a meta-analysis and systematic review2012 · 93 citations