Non-invasive left ventricular myocardial work calculated by pressure-strain loops provides diagnostic information beyond ejection fraction and strain by incorporating afterload.
Non-invasive measurement of myocardial work using pressure-strain loops provides valuable diagnostic information on myocardial efficiency, with potential applications in CRT patient selection.
Myocardial work is calculated from non-invasive left ventricular pressure and strain by speckle tracking echocardiography. Myocardial work provides diagnostic information beyond what is achieved from left ventricular ejection fraction and strain since it incorporates afterload, and provides a measure of myocardial efficiency. The method can be used to calculate global as well as segmental work. The work method was recently shown to be of clinical value in selection of patients for cardiac resynchronization therapy. Several other clinical applications are currently tested.
Smiseth et al. (Wed,) reported a review. Left ventricular myocardial work by pressure-strain loops was evaluated. Non-invasive left ventricular myocardial work calculated by pressure-strain loops provides diagnostic information beyond ejection fraction and strain by incorporating afterload.