Resulting from churning of cream, sweet buttermilk is a source of unique bioactive molecules capable of modulating cell signaling, lipid transport, metabolism, and immunity. Several in vitro and in vivo results provide support for the claim of the cholesterol-lowering action of buttermilk components. Clinical evidence now confirms the cardiovascular health benefits of short-term consumption of whole buttermilk, due most likely to its phospholipid content. Buttermilk consumption represents a natural way to manage blood pressure and blood lipids among healthy subjects. Peptides and polar lipids originating from the milk fat globule membrane are most likely responsible for the improved blood pressure and blood chemistry resulting from buttermilk consumption.
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Conway et al. (2014) studied this question.
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