Characterization of a mutation in the parE gene that confers fluoroquinolone resistance in Streptococcus pneumoniae

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Quinolone resistance locus nfxD of Escherichia coli is a mutant allele of the parE gene encoding a subunit of topoisomerase IV1997 · 123 citations
2. 2Cloning and characterization of the parC and parE genes of Streptococcus pneumoniae encoding DNA topoisomerase IV: role in fluoroquinolone resistance1996 · 155 citations
3. 3Quinolone resistance mutations in the DNA gyrase gyrA and gyrB genes of Staphylococcus aureus1994 · 158 citations
4. 4ParC subunit of DNA topoisomerase IV of Streptococcus pneumoniae is a primary target of fluoroquinolones and cooperates with DNA gyrase A subunit in forming resistance phenotype1996 · 227 citations
5. 5A novel gyrB mutation in a fluoroquinolone-resistant clinical isolate of<i>Salmonella typhimurium</i>1995 · 70 citations