Key result
A 14-year-old boy with Ewing sarcoma exhibited rapid systemic disease progression with widespread skeletal and CNS metastases within 4 weeks, notably without pulmonary involvement.
Why the study?
Ewing's sarcoma is an aggressive malignancy primarily affecting the skeletal system in children and young adults, and unusual presentations warrant reporting.
Case Report (n=1)
Reports an unusual case of Ewing sarcoma with rapid widespread skeletal and CNS metastasis but sparing the lungs.
May indicate need for early extrapulmonary imaging in pediatric Ewing sarcoma; extends known metastatic patterns but remains hypothesis-generating.
Introduction and importance Ewing's sarcoma is an aggressive malignancy primarily affecting skeletal system in children and young adults. CASE PRESENTATION: We report an unusual case of Ewing sarcoma in a 14-year-old boy with clinical and radiological features of rapid onset metachronous skeletal metastasis (within 4 weeks of diagnosis). CLINICAL DISCUSSION: Although the deterioration of symptoms was very rapid, it is unusual to note that in the presence of such widespread metastatic disease the lungs per se remained uninvolved. CONCLUSION: We describe a unique case of metastatic Ewing's sarcoma who showed rapid systemic disease progression with widespread skeletal metastases (and CNS involvement) but without any evidence of pulmonary involvement.
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Almarshad et al. (2022) conducted a case report in Ewing sarcoma (n=1). A 14-year-old boy with Ewing sarcoma exhibited rapid systemic disease progression with widespread skeletal and CNS metastases within 4 weeks, notably without pulmonary involvement.
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