Key result
Implementation of automated triggers (INR >3.0 and vitamin K orders) with staff education and therapy adjustments reduced overall warfarin-related adverse drug events by 39%.
Why the study?
Does the use of automated triggers (INR > 3.0 and vitamin K orders) combined with pharmacist interventions reduce adverse drug events in patients on warfarin therapy?
Observational
Yes
Does the use of automated triggers (INR > 3.0 and vitamin K orders) combined with pharmacist interventions reduce adverse drug events in patients on warfarin therapy?
Effect estimate: 39% reduction
Automated triggers using INR > 3.0 and vitamin K orders, combined with staff education and real-time therapy adjustments, significantly reduce warfarin-associated adverse drug events.
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May aid detection of warfarin ADEs via automated triggers in community hospitals; leaves open impact on outcomes and need for validation.
Hartis et al. (2005) conducted an observational in Warfarin-related adverse events. Automated triggers (INR > 3.0 and vitamin K orders) with staff education and therapy adjustments vs. Preintervention period was evaluated on Overall adverse drug events (ADEs) (39% reduction). Implementation of automated triggers (INR >3.0 and vitamin K orders) with staff education and therapy adjustments reduced overall warfarin-related adverse drug events by 39%.
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