Key result
Right atrial strain lower than 42.5% predicted a systolic pulmonary artery pressure > 37 mm Hg with 93% sensitivity, 94% specificity, and an AUC of 98%.
Why the study?
Can right atrial strain predict elevated systolic pulmonary artery pressure (>37 mm Hg)?
Observational (n=102)
Can right atrial strain predict elevated systolic pulmonary artery pressure (>37 mm Hg)?
Right atrial strain is a highly sensitive and specific echocardiographic marker for predicting elevated systolic pulmonary artery pressure.
Answers are grounded in this paper and cite their sources.
Suggests right atrial strain may offer a non-invasive marker for pulmonary pressures.
AIMS: Evaluate the ability of right atrial (RA) strain to predict systolic pulmonary artery pressure (SPAP). METHODS AND RESULTS: A total of 102 patients were prospectively enrolled. Conventional echocardiographic measures were performed. RA volume was calculated. Mean maximum right ventricle (RV) strain and lateral RA strain were obtained. Pearson's correlation test was used. A multivariate analysis was performed to compare SPAP with RA strain, RV strain, and baseline characteristics of the patients. RA strain was compared between patients with SPAP ≤ 37 mm Hg with those with SPAP > 37 mm Hg. A receiver operating characteristic (ROC) curve was constructed. A P < 0.01 value was considered statistically significant. AGE: 58.7 ± 15.7 years. Male: 46 (45.1%). The correlation coefficient between SPAP and RA strain was -0.64 (P < 0.01, 95% confidence interval (CI): -0.75 to -0.50). Quadratic R2 coefficient = 0.52. In the multivariate analysis, RA strain was independently associated with SPAP level. There were significant differences in RA strain between patients with SPAP ≤ 37 mm Hg (63.3 ± 13.3%; 95% CI: 59.4%-65.1%) and >37 mm Hg (32.7 ± 11.1%; 95% CI: 26.5%-38.39%) (P < 0.01). RA strain < 42.5% was capable to predict a SPAP > 37 mm Hg with 93% sensitivity and 94% specificity, area under the curve (AUC) of 98% (95% CI: 94%-100%). CONCLUSIONS: Right atrial strain is independently associated with SPAP level. RA strain lower than 42.5% can predict a SPAP > 37 mm Hg with high sensitivity and specificity.
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Deschle et al. (2018) conducted an observational in High systolic pulmonary artery pressure (n=102). Right atrial strain was evaluated on Prediction of systolic pulmonary artery pressure > 37 mm Hg (AUC 98%, 95% CI 94-100, p=<0.01). Right atrial strain lower than 42.5% predicted a systolic pulmonary artery pressure > 37 mm Hg with 93% sensitivity, 94% specificity, and an AUC of 98%.
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