Clinical and microbiological characteristics of reactive infectious mucocutaneous eruption: A case series of 5 patients

The clinical syndrome characterized by an acute mucositis, with variable involvement of the oral, ocular, and genital mucosa and minimal or absent skin involvement, has been described as “atypical Stevens-Johnson syndrome,” “Stevens-Johnson syndrome without skin lesions,” and “Fuchs syndrome.” In the past few years, a new nomenclature was introduced, mostly focused on the etiologic agent, Mycoplasma pneumoniae, including terms such as “Mycoplasma pneumoniae–associated mucositis”1,2 and “Mycoplasma-induced rash and mucositis”3; more recently, the concept of reactive infectious mucocutaneous eruption (RIME) has been proposed to act as an umbrella term including all mucosa-predominant acute parainfectious eruptions.