RubisCO catalysis has a significant impact on mitigating greenhouse gas accumulation and CO 2 conversion to food, fuel, and other organic compounds required to sustain life. Because RubisCO-dependent CO 2 fixation is severely compromised by oxygen inhibition and other physiological constraints, improving RubisCO’s kinetic properties to enhance growth in the presence of atmospheric O 2 levels has been a longstanding goal. In this study, RubisCO variants with superior structure-functional properties were selected which resulted in enhanced growth of an autotrophic host organism ( R. capsulatus ), indicating that RubisCO function was indeed growth limiting. It is evident from these results that genetically engineered RubisCO with kinetically enhanced properties can positively impact growth rates in primary producers.
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Satagopan et al. (2019) studied this question.
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