Viral upper respiratory infection at pediatric liver transplantation is associated with hepatic artery thrombosis

Viral upper respiratory infections (vURIs) are common in children. The effect of vURI at the time of liver transplantation (LT) on the postoperative outcomes is unknown. At a large quaternary referral center, preoperative viral screening tests by rapid enzyme immunoassay (EIA) and polymerase chain reaction (PCR) are performed routinely as patients present for LT, regardless of clinical appearance. Although a positive rapid EIA for respiratory syncytial virus (RSV) or influenza may preclude transplant, these screens are poorly sensitive. Moreover, the results of the molecular tests are often delayed and therefore cannot impact the clinical decision to proceed with organ transplant. The aim of this study is to begin to describe the impact of vURI on post-LT outcomes in children.