Key points are not available for this paper at this time.
Zoonotic diseases represent an important interface between socio-environmental change and public health, yet integrative assessments linking ecological and social determinants remain limited in tropical regions. This study mapped how socio-environmental drivers have shaped research patterns on zoonotic diseases in Brazil. We integrated socio-environmental data from empirical evidence with statistical modeling to evaluate temporal trends, thematic associations, and geographic distribution across six major zoonoses: leishmaniasis, Chagas disease, leptospirosis, yellow fever, Brazilian spotted fever, and hantavirus infection. Research output increased after 2010, particularly for leishmaniasis, Chagas disease, and leptospirosis, reflecting growing recognition of land-use change and socioeconomic vulnerability as key drivers of disease risk. Network analyses revealed strong thematic connections between zoonoses and land-use or socioeconomic factors, whereas climate change remained underrepresented. Spatially, research efforts were concentrated in the Amazon and Cerrado biomes, underscoring both ecological significance and persistent regional disparities in knowledge production. These findings demonstrate that Brazil’s zoonotic research landscape mirrors broader socio-environmental pressures, where deforestation, poverty, and climatic variability jointly influence disease dynamics. Strengthening geographically inclusive and environmentally informed research frameworks that integrate climate, land-use, and surveillance data will be essential to improve early-warning systems and guide sustainable, cross-sectoral public health policies.
Sousa et al. (Tue,) studied this question.