Key result
Decreased LVM is linked to sarcopenia, yielding ~0.83 predictive accuracy when combined with BMI.
Why the study?
Skeletal muscle mass and cardiac structure change with age, but it is unclear whether the loss of skeletal muscle mass is accompanied by a decrease in heart mass.
Is decreased left ventricular mass associated with sarcopenia and its severity in elderly inpatients?
Cross-Sectional (n=174)
No
Is decreased left ventricular mass associated with sarcopenia and its severity in elderly inpatients?
In hospitalized elderly patients, decreased left ventricular mass is associated with sarcopenia, and combining LVM with BMI has predictive value for the condition.
Answers are grounded in this paper and cite their sources.
May inform sarcopenia evaluation in hospitalized elderly; hypothesis-generating and requires prospective validation.
Objective: Skeletal muscle mass and cardiac structure change with age. It is unclear whether the loss of skeletal muscle mass (SMM) is accompanied by a decrease in heart mass loss. The aim of this study is to investigate the relationship of left ventricular mass (LVM) with sarcopenia and its severity in elderly inpatients. Methods: Seventy-one sarcopenia subjects and 103 non-sarcopenia controls were enrolled in this study. Bioelectrical impedance analysis, handgrip strength, and 5-time chair stand test were used to evaluate SMM, muscle strength, and physical performance, respectively. Myocardial structure and function were assessed by echocardiography. Sarcopenia was diagnosed according to the Asian Working Group for Sarcopenia criteria 2019. Conclusion: In hospitalized elderly patients, decreased left ventricular mass is associated with sarcopenia and its severity, and the combined measurement of LVM and BMI has a predictive value for sarcopenia.
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Liu et al. (2024) conducted a cross-sectional in Sarcopenia (n=174). Sarcopenia vs. Non-sarcopenia was evaluated on Presence of sarcopenia (predicted by combined LVM and BMI) (AUC 0.825, 95% CI 0.761-0.889, p=<0.001). In hospitalized elderly patients, decreased left ventricular mass was associated with sarcopenia, and the combined measurement of LVM and BMI predicted sarcopenia with an AUC of 0.825.
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