Key result
Citrate-fluoride-EDTA (CFE) tubes are recommended over fluoride-EDTA (FE) tubes for maternal glucose measurement in the diagnosis of gestational diabetes mellitus.
Why the study?
Does the use of CFE tubes compared to FE tubes improve the measurement of maternal glucose for the diagnosis of GDM?
Does the use of CFE tubes compared to FE tubes improve the measurement of maternal glucose for the diagnosis of GDM?
CFE tubes are recommended over FE tubes for maternal glucose measurement to diagnose gestational diabetes, likely due to better stability during the phlebotomy-cell separation interval.
Laboratories should adopt CFE tubes for GDM glucose testing; RCT evidence supports updating preanalytical guidelines.
we recommend that in contemporary obstetrics the use of FE tubes be replaced by CFE tubes for the measurement of maternal glucose for the diagnosis GDM. This is particularly important for the fasting sample because in reality the phlebotomy-cell separation interval is longest.
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Kavsak et al. (2016) studied this question. Citrate-fluoride-EDTA (CFE) tubes are recommended over fluoride-EDTA (FE) tubes for maternal glucose measurement in the diagnosis of gestational diabetes mellitus.
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