Editorial: Antioxidant potential of polyphenolic and flavonoid compounds

Antioxidant potential of polyphenolic and flavonoid compoundsIn ancient times and in the modern era, natural antioxidants have been known to play a vital role in promoting health and managing critical disease conditions (Gupta and Sharma, 2006).Plant-derived compounds like polyphenols and flavonoids possess remarkable antioxidant potential.These molecules have evolved in plants to counteract oxidative stress, and when consumed, they can confer similar benefits to humans (Bautista-Hernndez et al., 2021).This Research Topic, "Antioxidant Potential of Polyphenolic and Flavonoid Compounds," collected four studies that investigate the antioxidant properties of various plant species, including Dodonaea viscosa Jacq., Habenaria aitchisonii Reichb., Viola canescens Wall, and the enzymatic secretome of Botrytis cinerea.These studies demonstrate the significant antioxidant, anti-inflammatory, and antinociceptive activities of these plant-derived compounds, both in vitro and in vivo, and further testify to the international scientific community's interest in investigating beneficial natural compounds.The article entitled "In vitro and in vivo antioxidant therapeutic evaluation of phytochemicals from different parts of Dodonaea viscosa Jacq" contributes significantly to the expanding index of natural medicines by meticulously exploring the antioxidant potential of D. viscosa Jacq.(Plant-DV) (Khan et al.).Antioxidants are crucial in scavenging free radicals, thereby preventing cellular damage and contributing to the prevention and treatment of various diseases.In their study, the authors employed a comprehensive approach to evaluate the antioxidant properties of aqueous extracts from the leaves and flower-containing seeds of Plant-DV.By using both in vitro and in vivo methodologies, the researchers provide a holistic view of the antioxidant capabilities of this plant, underscoring its potential therapeutic applications (Dhaniya and Parihar, 2019).More into detail, the investigation involved a series of assays to measure glutathione (GSH) levels, hydrogen peroxide (H 2 O 2 ) scavenging effects, glutathione-S-transferase (GST) activity, and catalase (CAT) activity.Furthermore, the in vivo assessments performed on Wistar Albino rats, using vitamin C as a positive control, provided a solid comparative basis for evaluating the therapeutic potential of Plant-DV.Key findings from the study reveal that the flowercontaining seeds exhibit higher GSH content compared to the leaves in both normal and