APLI application: Small molecules and polymers can be analyzed quantitatively by using atmospheric-pressure laser ionization (APLI) coupled to time-of-flight mass spectrometry. This is realized by a derivatization strategy that facilitates selective ionization of polar and non-polar compounds in complex matrices without hyphenated techniques or stable-isotope-labeled standards.
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Schiewek et al. (2008) studied this question.
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