BACKGROUND: Propolis is a resinous material with complex chemical structure, produced by bees using plant sources, displaying a wide spectrum of biological activities. METHODS: Many studies have reported the use of this compound in pharmaceutical, medicinal, veterinary and dentistry areas, and the results have reported its pharmacological activities. RESULTS: Moreover, many propolis delivery systems have been proposed and evaluated, indicating that they can be used. On the other hand, considering its chemical and physical characteristics, propolis could be used as a material to produce micro/nano-structured pharmaceutical formulations. CONCLUSION: This work reviews the recent studies of development of micro/nanostructured systems using propolis or its byproduct. In addition, patents were reviewed and categorized.
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Bruschi et al. (2015) studied this question.
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