Iodine-Mediated Etching of Triangular Gold Nanoplates for Colorimetric Sensing of Copper Ion and Aptasensing of Chloramphenicol

A colorimetric method for fast, simple, and selective detection of Cu 2+ was developed using I – -mediated etching of triangular gold nanoplates (AuNPLs). The method was based on our finding that Cu 2+ efficiently promoted this etching in the presence of SCN – . The etching process was accompanied by a dramatic color change from blue to red, allowing for visual and spectroscopic detection of Cu 2+ with detection limits of 10 and 1 μM, respectively. When molecular recognition by a DNA aptamer was incorporated into this method, visual detection of chloramphenicol was also achieved with a detection limit of 5 μM.