Key result
Obesity shows no added surgical risk but links to ~25% lower mortality and more non-surgical complications.
Why the study?
Does obesity affect surgical complications, non-surgical complications, and long-term survival in patients undergoing esophagectomy for esophageal cancer?
Cohort (n=1,494)
Yes
Does obesity affect surgical complications, non-surgical complications, and long-term survival in patients undergoing esophagectomy for esophageal cancer?
In patients undergoing esophagectomy, obesity is associated with a higher risk of non-surgical complications like pulmonary embolism but better long-term survival compared to normal weight.
BMI may influence post-esophagectomy complications and survival; leaves open causal effects and practice change.
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Skogar et al. (2026) conducted a cohort in esophageal cancer (n=1,494). Obesity vs. Normal weight was evaluated on surgical complications (OR 0.92, 95% CI 0.62-1.39). Obesity was not associated with increased surgical complications (OR 0.92; 95% CI 0.62-1.39) but was linked to higher non-surgical complications and reduced all-cause mortality (HR 0.75).
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