New Catalyzed Three‐Component Cycloadditions for the Synthesis of Eight‐Membered Carbocycles

The sum always amounts to eight—Two new three-component [m+n+o] cycloadditions offer novel synthetic routes to eight-membered carbocycles (see scheme; m, n, o=4, 2, 2 or 5, 2, 1). The rhodium center serves as a template and brings three components into the necessary arrangement for the desired cycloaddition, thus enabling difficult-to-form eight-membered carbocyclic rings to be constructed in a single chemical operation with good atom economy.