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November 8, 2007Organic Letters158 citations

Gold-Catalyzed Intramolecular Carbocyclization of Alkynyl Ketones Leading to Highly Substituted Cyclic Enones

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TJTienan JinYYYoshinori Yamamoto

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Abstract

The reaction of the internal alkynyl ketones 1 (n=1) under the combined catalyst, AuCl3 and AgSbF6, gave the enones 2 in good to high yields, whereas that of the terminal alkynyl ketones 1 (n=0) under the combined catalyst, AuCl3 and AgOTf, afforded the cyclic enones 3.

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Cite This Study

Jin et al. (2007) studied this question.

synapsesocial.com/papers/6a5f785912cfc71cd85947d3https://doi.org/10.1021/ol702455v
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